Profile Subjects

Profiling subjects is a powerful way to view all of the data for one or more subjects, enabling you to view their entire history and determine potential causes for unexpected events or findings. Refer to the Profile Subjects process description for more information. A Profile Subjects action button is available in the Results windows from many JMP Clinical processes as well as in the Subject Utilities menu.

Note: As of JMP Clinical 4.1, this process has been renamed Profile Selected Subjects. Also introduced in 4.1 is the Profile All Subjects variant.

Important: Before clicking this action button, a JMP table with a Unique Subject Identifier column must be open and in focus and you must select the subjects of interest by clicking in a graph or selecting rows in the corresponding table.

For example, run the DM Distribution process for the Nicardipine study and select subjects less than 20 years old from the Age distribution histogram. Clicking the Profile Subjects action button then generates the window shown below. Output is organized into panes and tabs. Each tab contains one or more plots, data panels, data filters, or other elements that facilitate your analysis.

The Profile Subjects window contains the following elements:

Panes

These panes contain options that enable you to customize the profiles that are generated. Click the triangle ()next to each pane to expand that pane.

•	Subjects pane

This pane enables you to select which subjects to profile. Hold the Ctrl key to select multiple subjects or the Shift key to select contiguous subjects among those listed. Shown below is a partial Profile display (artificially condensed) for three selected subjects.

•	Templates pane

Templates enable you to control display of specific domain elements and colors along with other attributes such as display mode and frame sizes. Click the triangle ()to expand the pane.

Use the Active Template drop-down menu to select a template.

Click Create or Update a Template to open the Create or Update a Template window. Select a domain and use the buttons (circled below) to change that domains position in the profile, alter the color scheme, or change the figure labels.

Click Delete Templates to selectively remove templates.

•	Domains pane

These options enable you to control exactly what data are displayed in the profiles. Click the triangle ()to expand the pane and view the domains. Click on the triangle next to a domain (Medical History, for example) to expand it, and use the check boxes to remove or add items. Uncheck All and Check All buttons (circled)are available for removing or adding entire domains.

•	Data Tables pane

Use this pane to select and view one or more of the underlying data tables for the profiles. Click the triangle () to expand the pane and reveal the data tables.

Click one of the buttons (Profile, in this example) to view the corresponding table. Points selected in any of the graphs appear as highlighted rows in the tables.

•	Findings Pane

This pane contains options for specifying how numeric measurements are presented and to control the degree of detail shown for findings domains.

Use the Numeric Measurement options to specify how numeric results are presented.

Use the Display Mode options to control the degree of detail presented.

The Compressed mode saves vertical space by collapsing values that have been grouped into a single row. (You must create an XXgrp.sas7bdat for the grouping to occur.) In the example above, note the groupings for labs such as POTASSIUM / SODIUM and ALT / AST. Note a slight shift in the x-axis time value is used for visual clarity of groupings.

The Normal mode allocates one row for each value, using more vertical space but aligning all measurements exactly on the x-axis time scale. Both the Compressed and Normal modes include mini color legends on the right hand side of the display. The scale of these legends changes for each value.

The Expanded mode creates spark line plots for each row, using even more vertical space but informative for clearly visualizing time trends. This mode is shown below.

Profile Frame Size

This pane lets you control the vertical and horizontal space allocated to the primary subject profile view. Use the sliders to suit your screen size and resolution. Right-click the sliders to change their range.

Medical History Frame Size

This pane lets you control the vertical and horizontal space allocated to the primary subject profile view. Use the sliders to suit your screen size and resolution. Right-click the sliders to change their range.

Tabs

The following tabs are generated by this process:

•

General.

•	Demographics.

Tab Viewer

This pane provides you with a space to view individual tabs within the Results window.

Action and Miscellaneous Buttons

Action buttons provide you with an easy way to drill down into your data or perform subsequent analyses. The following action buttons are generated by this process:

•	Generate Report: Click to create a PDF or RTF version of the profiles. Several options are available after clicking the button, as shown below.

•	Create Narratives: Click to launch the AE Narrative process on the currently selected subjects. It automatically creates an English written description of the adverse events and related data for these subjects.

•	View Comments: Click to display all comments from the CO domain for the currently selected subjects.

•	Create Subject Filter: Click to create a filter that can be applied in subsequent analyses to reduce the analyzed subjects to only the ones currently selected.

•	Add Notes: Click Add Notes to open a text box where you can record specific notes for selected subjects.

•	View Notes: Click View Notes to open a JMP table containing all of the notes recorded for the selected subjects.

•	Close All: Click to close all graphics windows and underlying data sets associated with the output.