Identify the cause of nonlinear effects while avoiding confounding any terms up to second order. So not only can you detect nonlinearity, as you might with center points in a traditional screening design, but you can identify the responsible factors.
For details, see Structure of Definitive Screening Designs. For information about definitive screening designs with blocks, see Blocking in Definitive Screening Designs. For suggestions on how to analyze data obtained using definitive screening designs, see Analysis of Experimental Data.

Help created on 9/19/2017