Definitive Screening Designs
Definitive screening designs work for factor screening if you have any combination of continuous or two-level categorical factors. These designs are particularly useful if you suspect active two-factor interactions, or you suspect that a plot of a continuous factor’s effect on the response might exhibit strong curvature.
Definitive screening designs are small designs. For six or more factors, there are only about twice as many runs as factors. Yet, they often conclusively identify which of several factors affect the response. In particular, they can detect and identify any factors causing strong nonlinear effects on the response.