In experiments on systems where there is substantial random noise, the goal is to minimize the variance of prediction. In experiments on deterministic systems, there is no variance but there is bias. Bias is the difference between the approximation model and the true mathematical function. The goal of space-filling designs is to bound the bias.
The Space Filling designer supports the following design methods:
The Fast Flexible Filling method forms clusters from random points in the design space. These clusters are used to choose design points according to an optimization criterion. This is the only method that can accommodate categorical factors and constraints on the design space. You can specify linear constraints and disallowed combinations. See Creating and Viewing a Constrained Fast Flexible Filling Designand see FFF Optimality Criterion.