Output Overview Descriptions | Clinical Reports | Findings Bubble Plot

Findings Bubble Plot
This report tracks a pair of findings measurements over time with an animated bubble plot . Values are linearly interpolated over time. You can select subjects of interest and display their time profiles.
For the LB domain, lab measurements are standardized by a reference midrange derived from the lower limit of normal (LLN) and upper limit of normal (ULN) to facilitate comparisons. The standardization centers the values at the midpoint between the LLN and the ULN and scales by (ULN - LLN)/2.
Refer to the Findings Bubble Plot requirements description for more information.
Note : JMP Clinical employs a special protocol for data including non-unique Findings test names. Refer to How does JMP Clinical handle non-unique Findings test names? for more information.
Running Findings Bubble Plot with the Nicardipine sample setting and LB findings domain generates the tabbed Results window shown below.
Note : For this example, an Ending Time Value of 14 was entered on the Display portion of the Options dialog because most measurements were taken only in the first two weeks of the study.
The Report contains the following elements:
Bubble Plot of LB : This tab displays a JMP Bubble Plot of findings values for each subject in a study that can be animated to view findings measurements across the study days or weeks of a trial. Note that the name of the tab is dependent on the current findings domain being analyzed. The tab is named " Bubble Plot of XX " where XX is the domain specified on the dialog .
Data Filter
This enables you to subset subjects based on demographic characteristics and other factors. Refer to Data Filter for more information.
Drill Down Buttons
Drill down buttons, provide you with an easy way to drill down into your data. The following drill down buttons are generated by this process:
Profile Subjects : Select subjects and click to generate the patient profiles. See Profile Subjects for additional information.
Profile Subjects : Select subjects and click to open the ADSL (or DM if ADSL is unavailable) of selected subjects.
Cluster Subjects : Select subjects and click to cluster them using data from available covariates . See Cluster Subjects for additional information.
Create Subject Filter : Select subjects and click to create a data set of USUBJID s, which subsets all subsequently run processes to those selected subjects. The currently available filter data set can be applied by selecting Apply Subject Filter in any process dialog .
Graph Time Trends : Select one or more points on the bubble plot and click the , as shown below, to drill down to a Trellis Plot for each subject selected.
Initially, the plots display the two Findings tests that were shown on the X -axis and Y -axis in the original bubble plot on the Y -axis (in this case ( BILI and ALT levels), as shown below.
You can select more Findings tests to add to the Y -axis by clicking in the Variables panel on the left side of the plot and dragging selected tests to the right of the Y -axis of one of the subject plots. For example, you can select ALP and AST by clicking on ALP , then while holding Ctrl , also click AST and drag them both over until the light blue box appears as in the following figure:
Click to generate a standardized pdf - or rtf -formatted report containing the plots and charts of selected sections.
Click the Options arrow to reopen the completed process dialog used to generate this output.