Output Tab Descriptions | Clinical | Summary Statistics Volcano Plot

Summary Statistics Volcano Plot
This section can differ depending on the type of analysis you perform.
Analysis of Mean or Variance
If you specify either Mean or Variance, you generate a volcano plot similar to that shown below:
This section contains the following elements:
One Data Filter .
Enables you to subset subjects based on country of origin, study site and/or Test. Refer to Data Filter for more information.
The volcano plot is used to determine the deviation of a mean or variance for Findings tests at a site versus other sites. Each point represents a single Findings test for a specific site. Here, the x -axis represents the standardized difference in means between each between the site and the reference set (all other sites). For comparisons of variances, the x -axis represents the log 2 (Ratio of Variances) between the site and the reference set. -log 10 ( p -values) are plotted on the y -axis. While most of the findings are close to the means across all of the sites. some of the points lie farther to the right or left of 0, indicating larger differences between the site and the reference set.
You can mouse over points of interest to see their labels or select points by dragging a mouse rectangle over them (as shown above). Selected rows are highlighted in other plots and you can also then click on various Drill Down Buttons for further analyses on those specific sites. In this example, point skewed to the right is selected and the corresponding row is viewed in the following subset.
The mean systolic blood pressure findings at this site average 13 points higher than the other sites. This finding might warrant further investigation.
Analysis of Skewness or Kurtosis
If you specify either Mean or Variance, you generate a volcano plot similar to that shown below:
This section contains the following elements:
One Data Filter .
Enables you to subset subjects based on country of origin, study site and/or Test. Refer to Data Filter for more information.
This plot shows the ratio of skewness or kurtosis from site to reference, with bubbles size by # of measurements. Values far from 1 on y -axis indicate large differences which may warrant further exploration, though bubbles of small size (low sample size) may represent random noise.
You can mouse over points of interest to see their labels or select points by dragging a mouse rectangle over them (as shown above). Selected rows are highlighted in other plots and you can also then click on various Drill Down Buttons for further analyses on those specific sites.