Volcano Plots

The Volcano Plots tab contains the following elements:

•	Two Volcano Plots .

The y -axis represents the -log 10 (raw p-value ) from either the Log-Rank test ( left ) or the Wilcoxon test ( right ). In most instances, these two tests coincide. To interpret this axis, consider that

1. a p -value of 1 equals 0 on the -log 10 scale,

2. a p -value of 0.1 equals 1 on the -log 10 scale,

3. a p -value of 0.01 equals 2 on the -log 10 scale,

4. a p -value of 0.001 equals 3 on the -log 10 scale,

5. a p -value of 0.0001 equals 4 on the -log 10 scale.

The x -axis represents the maximum computed distance between the two curves, and color indicates which treatment was likely to have the event sooner. For example, Phlebitis occurs at approximately 0.27 on the x -axis and is green . This means that at least one time point in the Kaplan-Meier and Hazard Plots , the risk of having this particular event was 27% more likely for Nicardipine versus Placebo.

Events above the dotted red line are considered statistically significant after adjusting for multiple comparisons. Adjustment is applied using the linear step-up method of Benjamini and Hochberg (1995) to control the false discovery rate.

See Volcano Plot for more information.