Parameters | Workflows | Select Method

Select Method
Use the drop-down option to select a method to calculate a subset of features that exhibit high cell-to-cell variation in the data set.
It has been reported that focusing on that exhibit high cell-to-cell variation in downstream analysis helps to highlight biological signal in single-cell data sets.
Two methods, Dispersion and VST, are included in this workflow. The Dispersion method is based on the mean.var. plot in the Seurat package. VST is based on a Loess fitting method which is also described in Seurat.
Please check and Comprehensive Integration of Single-Cell Data at for more information.