Weighting Method for Sibships

Use this parameter to specify the method for dealing with sibships containing more than two affected individuals.

Available methods are described in the table below:

Method:

Specify this method to:

treat all sibpairs as independent

Apply no weight to the tests.

apply Suarez weights

Specify the application of a weight of 2/a where a is the number of affected siblings in the sibship (Suarez and Hodge, 1979), to all the affected sib-pairs from a sibship.

Note: If all sibships are of size 2, the methods are equivalent.

To Specify the Weighting Method

8 Select the desired method by clicking within the appropriate radio button.