Collapse rare variants within analysis group

Check this box to combine rare variants within a gene (or other unit, as defined by the Annotation Analysis Group Variable) and specify coding as 1 if any rare allelesare present in any SNP belonging to the gene or group, and 0 otherwise.

If not checked, rare variants are coded individually according to a dominant model, that is, 1 if any rare alleles are present in the SNP, and 0 otherwise.

To Collapse Rare Variants within Analysis Group:

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Ensure that the box is checked.