Output Overview Descriptions | Clinical | Cluster Subjects Across Study Sites

Cluster Subjects Across Study Sites
Running this process for Nicardipine generates the tabbed Results window shown below. Output from the process is organized into tabs. Each tab contains one or more plots, data panels, data filters, and so on. that facilitate your analysis. This report uses pre-dosing information with the goal of identifying subjects that have enrolled at two or more clinical sites.
Tabs
This pane enables you to access and view the output plots and associated data sets on each tab. Use the drop-down menu to view the tab in the Tab Viewer pane, open the tab in a new window, or remove the tab and its contents from the Tab Viewer pane.
The following tabs are generated by this process:
Between-Subject Distance Summary (Cluster Subjects Across Study Sites): Box plots are presented for all pairwise distances between subjects in the selected population. Pairs are limited based on selections from the Cluster subjects matching these criteria panel of the dialog.
In this example, box plots are presented by gender and race. The more similar a pair of subjects, the smaller the distance value (a zero indicates a perfect match). The minimum distance from each covariate subgroup is presented in the box plot to the right. The subgroup with the most similar pair of subjects is presented on the next tab.
Subgroup Clustering: Only one tab is opened in the Tab Viewer pane. The name of this tab is dependent on the covariate values used (as specified in the Cluster subjects matching these criteria panel) and the subgroup that is identified with the minimum pairwise distance.
In this example, the Sex =F, Race WHITE subgroup shows the minimum pairwise distance. Other subgroup results can be opened from the Tabs menu.
Tab Viewer
This pane provides you with a space to view individual tabs within the Results window. Use the tabs to access and view the output plots and associated data sets.
Drill Down Buttons
Drill down buttons provide you with an easy way to drill down into your data. The following drill down buttons are generated by this process:
Profile Subjects: Select subjects and click Profile Subjects to generate the patient profiles. See Profile Subjects for additional information.
Show Subjects: Select subjects and click Show Subjects to open the ADSL (or DM if ADSL is unavailable) of selected subjects.
Show Rows in Heat Map: Select points that represent pairs of subjects in the Box Plots and click Show Rows in Heat Map to highlight the subjects within the Heat Map and Dendrogram to see how they cluster together.
Subset Clustering: On a subgroup clustering page, subsets clustering to subjects, based on pairs selected from corresponding box plot.
Revert Clustering: Returns a subset clustering to the original state where all subjects are clustered.
Output Data
This pane provides links to the following output data sets:
Cluster Subset Summary Data Set: This output data set contains a complete list of the adverse events significant by one or more criteria.
Note: You can view the data in a file or data set by clicking either Open or View Subset (when the data set is very large).
For detailed information about the files and data sets used or created by JMP Life Sciences software, see Files and Data Sets.
General
Click View Data to view the associated data table. Refer to View Data for more information.
Output includes one summary data set (named csass_sum_XXX1, by default) containing one record per subject with pre-dosing data, one data set of all pairwise distances within the covariate subgroups (named csass_alldist_XXX, by default), one data set containing minimum pairwise distances for each covariate subgroup (named csass_mindist_XXX), by default), one data set per covariate subgroup containing pairwise distances (named csass_p_Y_XXX, by default, where Y is indexed 1 to the number of covariate subgroups) and one data set per covariate subgroup containing the distance matrix of subjects within the covariate subgroup (named csass_Y_XXX, by default, where Y is indexed 1 to the number of covariate subgroups).
Click Reopen Dialog to reopen the completed process dialog used to generate this output.
Click Create Report to generate a standardized pdf- or rtf-formatted report containing the plots and charts of selected tabs.
Click Add Notes to take notes, and store them in a central location. Refer to Add Notes for more information.
Click View Notes to read user-generated notes. Refer to View Notes for more information.
Click Close All to close all graphics windows and underlying data sets associated with the output.
Add Holiday or Event
Refer to Add Holiday or Event for a description of the output data and files generated by this process.

1
The _XXX designation is used to designate a one- to three-digit number that is added sequentially to prevent overwriting of existing data sets.