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In this example, you find a compromise between an 8-run main effects only design (see Design That Estimates Main Effects Only) and a 22-run design capable of fitting all the two-factor interactions. You use Alias Optimality as the optimality criterion to achieve your goal.
1.
Select DOE > Custom Design.
2.
Type 6 next to Add N Factors.
3.
Click Add Factor > Continuous.
4.
Click Continue.
5.
Select Optimality Criterion > Make Alias Optimal Design from the red triangle menu.
6.
Click User Specified and change the number of runs to 16.
Figure 5.9 Factors, Model, Alias Terms, and Number of Runs
Note: Setting the Random Seed in step 7 and Number of Starts in step 8 reproduces the exact results shown in this example. In constructing a design on your own, these steps are not necessary.
7.
(Optional) From the Custom Design red triangle menu, select Set Random Seed, type 1692819077, and click OK.
8.
(Optional) From the Custom Design red triangle menu, select Number of Starts, type 161, and click OK.
9.
Click Make Design.
10.
Open the Design Evaluation > Alias Matrix outline.
Figure 5.10 Alias Matrix
11.
Open the Design Evaluation > Color Map on Correlations outline.
Figure 5.11 Color Map on Correlations

Help created on 3/19/2020