Differential Expression

Click on a button corresponding to an expression modeling process. Refer to the table below for guidance.

Process

Choose this process for...

One-Way ANOVA

Fitting a one-way repeated-measures ANOVA linear model to rows of the input data set, using all combinations of different effects as distinct groups

Tip: To examine all possible effects and their interactions separately, choose the ANOVA process instead.

ANOVA

Fitting an analysis-of-variance linear model to sequential rows of the input data set, allowing for h hypothesis testing on all possible effects of each of the variables and interactions separately

Caution: These processes can be computationally intensive for large data sets.

Mixed Model Analysis

Fitting a mixed linear model on a row-by-row basis to pre-normalized data and creating numerous output displays, with maximum sophistication and flexibility

Note: You must understand SAS PROC MIXED syntax to use this process.

Survival Analysis

Testing association of each normalized input data set row with a censored response, fitting a Cox proportional hazards model on a row-by-row basis

Allele Specific Expression Filter

Screening for potential allele-specific expression, using both DNA and RNA intensity data

Estimate Builder

Constructing customized linear hypothesis tests in the form of SAS ESTIMATE statements

Tip: These statements can be saved in a file and used in ANOVA and Mixed Model Analysis (and in Workflows using these processes) to test an arbitrary set of linear hypotheses regarding the relative importance of different combinations of fixed effects parameters.

Difference Chooser

Quickly and easily selecting LSMeans fixed effect level differences

Tip: These differences can be saved in a file and used in ANOVA and Mixed Model Analysis (and in workflows using these processes)

Two-Way Plotter

Drawing HTML line plots and bar charts for selected rows of a tall data set and two selected experimental design variables, in order to visualize the effects of individual experimental factors, or to detect possible interactions between experimental factors for a given gene or set of genes

See Expression for other subcategories.